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DNA Extraction Systems (DNA, RNA and Proteins)

Hudson Robotics equipment

DNA Extraction Systems (DNA, RNA and Proteins)

Hudson Robotics has introduced an automated DNA extraction system as another member of our expanding catalog of powerful systems designed to support genetic research efforts.  Our DNA extraction system greatly simplifies the process of isolating pure nucleic acids and/or proteins from a wide variety of natural sources.  

These laboratory workcells are built around our PlateCrane EX or our SciClops™ robot arm for hours of hands-off processing time. The workcells can utilize Hudson’s family of liquid handling instruments or 3rd party manufactures liquid handling instruments which all can be controlled by our powerful SoftLinx automation software. The Extraction System is packed with enhancements and features.  

Support your favorite approach to DNA, RNA and Protein Extraction

  • Choose from well-known vendor kits, such as Norgen and Promega
  • Run filtrations using vacuum, the FilterPress for positive pressure and/or magnetic beads
Offer powerful options to fit into your pipeline
  • Optional integrated thermocycler allows direct PCR amplification
  • One system extracts DNA, RNA and Proteins from Soil, Plants, Blood, etc.

Highly flexible software that’s easy-to-use: Automated DNA Extraction System
  • Based on our popular flow chart-based SoftLinx automation system
  • Wizards allow technicians to choose which extraction they’ll run. A single screen then helps them set up their samples and plates.
  • Part of Hudson’s new GO Technology

Integrated centrifuge allows complete automation of the entire process. 
  • Run multiple plates of samples by machine without user intervention.
  • Low-temperature storage systems can be integrated into the system

The extraction system has been designed to run commercial kits that extract DNA, RNA and proteins from a variety of sources including:

  • Soil
  • Plants
  • Bacteria
  • Blood
  • Urine
  • Saliva
  • and more…

The system can be configured with any one, or all, of your favorite separation methods, including:

  • vacuum filtration
  • pressure filtration
  • magnetic bead separation
  • centrifuging

The utility of the extraction system can be greatly enhanced by adding additional equipment in range of the robot arm to add direct downstream processing of the purified bio-molecules.  Here are some examples of the potential versatility of combining the extraction system with additional equipment:

  • Thermocycler: Direct amplification of the extracted and purified DNA (PCR).  
  • UV Spectrometer: Measure the concentration of purified proteins.
  • Dynamic Light Scattering (DLS) reader: Measure the size and/or state of aggregation of each sample.

The following is a short list of other applications that can be carried out on the standard extraction system:

DNA Extraction

DNA Extraction

DNA/RNA/Protein Extraction – Isolate pure DNA from the cell.  There are a wide variety of protocols available for isolating pure DNA from all sorts of material.  But they all involve the same four basic steps: lysis, adsorption, washing and elution.  The details vary, depending on the source material and the concentration of DNA expected.

Microbiome/Microbiota Research

Microbiome/Microbiota Research

Hudson Robotics can help researchers that are studying the microbiota (gut microbiome) in anaerobic chambers with its small form factor, automated tools for bacterial colony-picking, sample preparation, DNA extraction, plasmid preparation and DNA normalization. Research on Gastrointestinal disorders, Infectious diseases, metabolic disorders, immunology, oncology and CNS are all possible using Hudson technologies.

Oligo Purification

Oligo Purification

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DNA and RNA Normalization

DNA and RNA Normalization

Utilizing the simplicity of Hudson’s SOLO, and SoftLinx Software, users perform accurate DNA normalization of any plate of DNA samples.  Using the SOLO to perform all the solvent addition, mixing and sample transfer operations, the user selects a DNA quantification file, and starts the system.

Protein Expression & Purification

Protein Expression & Purification

Hudson offers a wide range of instrumentation to support the entire range of protocols commonly encountered when preparing peptides and proteins.  From liquid handlers to support PCR through vast, multi-component systems to support an entire research effort.

Serial Dilutions

Serial Dilutions

A key step to quantify concentration-dependent affects.  A step-wise dilution of a sample through a series of pipette aspirations/dispenses.  Automating this process is essential to maximize the accuracy of the resulting data.

Here’s a short demo of some of the functionality of the Extraction System:

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