Synthetic Biology Workstation
Synthetic Biology
Hudson Robotics’ unique capabilities and product mix have enabled us to lead the entire world in lab automation of the complete Synthetic Biology Pipeline: from automated oligo synthesis and gene assembly through transformation, colony picking and plasmid preparation.
Combined with our previous experience with protein expression and purification systems, Hudson can now offer solutions for automating any process encountered in a typical molecular biology laboratory.
Learn more about our automated solutions for each of the following steps of the Synthetic Biology Pipeline.
| Synthetic Biology Pipeline |
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Protean Workcell
SOLO Liquid Handler
RapidPick Complete Colony Picker
Bio-Rad CFX96 (qPCR)
Biometra TRobot
Bioautomation MerMade Integration
RapidPick Lite Colony Picker
RapidPick MP: 20 Pin Colony Picker
RapidPick SP Single Pin Colony Picker
RapidPick Harvester
inheco ODTC 96
Roche LightCycler Integration
Useful Links
External
The Synthetic Biology Project at the Wilson Center
The Synthetic Biology Center at MIT
Hudson Robotics
- Genetic Transformation Systems in Fungi, Volume 2 – Includes a chapter (16) entitled “Integrated Automation for Continuous High-Throughput Synthetic Chromosome Assembly and Transformation to Identify Improved Yeast Strains for Industrial Production of Biofuels and Bio-based Chemicals ,” written by Hudson Robotics and the USDA
- “Systems and Methods for Automated Proteomics Research,” US 20070184546 A1 – Our US patent on the first integrated workcell to support the assembly and expression of modified genes
- Design and Construction of a First-Generation High-Throughput Integrated Robotic Molecular Biology Platform for Bioenergy Applications
- High-throughput screening of cellulase F mutants from multiplexed plasmid sets using an automated plate assay on a functional proteomic robotic workcell
Video
Transformation and Colony Plating
| This video shows automated bacterial transformation and colony plating using the Hudson SOLO Pipettor. |
DNA Normalization
| In the following video, DNA Normalization is carried out on the SOLO pipettor |
Colony Plating
| In the following video, the SOLO plates 12 colonies at a time directly onto a Petri Dish. This is part of a system developed for the USDA. |
Colony Picking
| This video shows the RapidPick ACIS in action which colonies to be picked are stored in a Liconic incubator. |
| In this video, the RapidPick is being used to pool several dye samples |
| Colonies can also be picked with the SOLO pipettor. This video shows fungal colonies being selected from a Petri dish with a single-channel SOLO |
| This modified RapidPick system was designed to inoculate 2 different destination plates with each picked colony |