Call (973) 376-7400 Request a Quote
Ahead of the Curve.

Protein Expression & Purification

Hudson Robotics equipment

Protein Expression & Purification

Hudson has automated the entire process of protein expression of experimental genes, whether they are from random mutagenesis or from directed assembly.  We offer a wide range of instrumentation to support the entire range of protocols commonly encountered when preparing peptides and proteins.  From liquid handlers to support PCR through vast, multi-component systems to support an entire research effort.

Ligation – Where bacteria or yeast re to be used for protein expression, Hudson’s automated ligation process moves the desired DNA inserts onto growth or expression vectors prior to transforming them into the competent cells.  The systems can utilize kit-based or user-developed protocols.

Transformation – Using programmable dry-bath nests, the system prepares cells for transformation then executes this on a SOLO pipettor using the insert-containing vectors.  Again, the systems can utilize kit-based or user-developed protocols.

Fully-automated ProLink Protein Expression System

Transcription – Hudson has developed automated transcription workcells for RNA production directly from DNA samples.  Flask-based reactions yield up to 40ng.

Colony Picking – Hudson’s RapidPick automated colony picking systems can be operated as a standalone application or as part of larger cell-culturing and protein expression systems.

Colony to qPCR – Available as stand-alone workcells, or integrated into cell-based assay systems,  SoftLinx directs the preparation and processing of cells directly from colonies to qPCR.   The colony-to-qPCR reaction can be fed directly to a Roche LightCycler, Bio-Rad CFX or ABI 7900/ViiA7 qPCR instruments.

Mini-Prep – Fully-automated separation and purification of plasmids or expressed proteins.

Mini-Prep Workstation

 

SOLO Liquid Handler

SOLO Liquid Handler

The Hudson SOLO™ liquid handling robot is an automated pipettor that can do anything expected of a hand-held pipettor perfectly, at about half the cost of other laboratory robotics platforms, without human error. The Solo works well below 1ul (1-3ul CV=1%; 0.25ul CV=4%). The Solo will fit into most biological safety cabinets and fume hoods. The SOLO can be loaded and operated manually, but is also compatible with robot loading systems from most manufacturers, including our PlateCrane EX.

ProLink Express

ProLink Express

The ProLink Express represents a breakthrough in integrating laboratory instruments that has changed the way researchers use automation. It is the first fully automated proteomics workcell. that integrates all plate delivery and transfer operations with complete data tracking. It automates the entire protein expression process, from initial bacterial colony picking through final protein expression and measurement. The ProLink Express system is capable of delivering a plate to any of its instruments from any other instrument, in any order and simultaneously with other processes.

RapidPick Complete Colony Picker

RapidPick Complete Colony Picker

Hudson’s RapidPick™  Colony Picking Systems are the only fully automated high-throughput colony picking workcells. They deliver performance and precision unparalleled in the Life Science industry.  In addition to allowing researchers to automate the selection and growth of cells grown on a colony plate, they also retain a record and image of each specific colony and which culture plate/well it inoculated.

PlateCrane EX Microplate Handler

PlateCrane EX Microplate Handler

Rugged and reliable, the Plate Crane makes it easy to automate plate feeding to any of hundreds of supported instruments. Many configurations are available to support your application, and it even fits in a standard hood!

Automated Synthetic Biology

Automated Synthetic Biology

Hudson Robotics’ unique capabilities and product mix have enabled us to lead the entire world in the automation of synthetic biology:  from automated oligo synthesis, through to fully- automated protein expression.

Hudson’s ability to move microplates and control instruments has enabled us to build completely automated  gene-assembly systems, and hands-free protein expression systems, in compact work envelopes that no other automation company in the world can duplicate.  

In addition to the compactness of Hudson’s systems, we also offer another unique feature:  the ability to use only portions of the entire system at any time.  This allows the researcher to perform only one or two steps of the process as needed. 

Hudson has also coupled our internet-based system controller to allow researchers to download their workflow from the cloud.  Now, it doesn’t matter if the scientist is in the next room, on the next continent.  Hudson’s systems can react and run synthetic biology processes on demand.

Biometra TRobot

Biometra TRobot

Hudson has developed a plugin for the Biometra TRobot thermocycler.  This integration has been incorporated into a number of workstations that require a PCR step as part of the supported application pipeline.

DNA Extraction Systems (DNA, RNA and Proteins)

DNA Extraction Systems (DNA, RNA and Proteins)

Hudson Robotics has introduced DNA extraction designs  to enhance our expanding catalog of powerful systems to support genetic research efforts.  Our DNA extraction system greatly simplifies the process of isolating pure nucleic acids and/or proteins from a wide variety of natural sources.

RapidPick Lite Colony Picker

RapidPick Lite Colony Picker

The RapidPick ‘Lite’ offers all the capacity, throughput and picking/re-arraying features of the RapidPick Complete, but without  the liquid dispenser or  microplate sealer. The RapidPick Lite averages 2,400 colonies per hour.

OB-1 Robotic Lab Assistant

OB-1 Robotic Lab Assistant

A collaborative effort between Hudson Robotics and Obotics, this workcell supports a wide variety of sample preparation functions, including SPE/SLE processing, hydrolysis and derivativization, with all of the requisite microplate and liquid handling features required to automate the entire process.

RapidPick Basic Colony Picker

RapidPick Basic Colony Picker

The RapidPick Basic  consists of the RapidPick MP colony-picking instrument only.  The RapidPick MP is the fastest, most accurate automated multi-pin colony picking system in the world.  The RapiPick MP is at the heart of the Complete and Lite systems which include robotic plate loading, media filling as well as other features, such as plate sealing in the RapidPick Complete Workcell. 

The RapidPick Basic unit is intended for researchers who need the accuracy and high outgrowth rates of the RapidPick colony-picker, but whose workload doesn’t require the added automation available in the Complete or Lite systems.    

RapidPick Harvester

RapidPick Harvester

Hudson Robotics has developed a unique, automated picker for microbial and fungal samples in microplates or omnitrays.  The RapidPick Harvester™ identifies and extracts sample plugs of stem cell clusters, microbial colonies, or fungal samples grown on agar or in semi-solid media.

Promega GloMax® Integration

Promega GloMax® Integration

Our plug-in supports the new Promega GloMax® multi-mode reader.  We’ve used this integration as part of automating several of Promega’s luminescence-based assays, as well as various absorbance and fluorescence-based protocols.

FilterPress™ DNA, and RNA, Extraction

FilterPress™ DNA, and RNA, Extraction

Hudson Robotics introduces the FilterPress, a powerful alternative to vacuum nests, magnetic beads and centrifuges for automated DNA Purification, Plasmid Preps, and Solid Phase Extraction of any kind. It does the same job as a vacuum manifold, but it’s capable of higher pressure than vacuum, useful for difficult samples. The FilterPress is fully articulated, so you can walk away. And if you’re used to vacuum, you’ll probably find it much less messy.

inheco ODTC 96

inheco ODTC 96

Hudson has developed a plugin for the inheco ODTC 96 thermocycler.  This represents another integration that has been incorporated into workstations that require a PCR step as part of the supported application pipeline.

Request a Quote