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ARI Crystal Gryphon

A small, fast, and affordable option for setting up all of your protein crystallization plates.

The ARI Crystal Gryphon protein crystallization pipettor fits into tight lab spaces and tight lab budgets. The Gryphon head uses no disposable tips, so the cost of operation and environmental waste is minimized.

Description

The Gryphon Family is an industry-leading family of robotic pipettors designed specifically for protein crystallography.  With unsurpassed reliability, performance, and speed, the Gryphon is the ideal protein crystallization pipettor for drop-setting all of your crystallization assays.

Why Choose a Gryphon?

  • Evaporation is not an issue with the dual-dispense heads of the Gryphon. A 96-well LCP plate can be sealed in one minute, and a vapor diffusion plate in under one minute.
  • Versatile and upgradable. Add a nano or LCP/Seeding dispenser at any point in the future.
  • Set up LCP, seeding, sponge phase, bicelle, sitting drop, hanging drop, and microbatch assays all in one system.
  • Dispense 96 buffers simultaneously and achieve reproducible results due to minimal volatile buffer evaporation.
  • A 96-well LCP plate can be sealed in under 2 minutes and a vapor diffusion plate in under 1 minute.
  • One instrument transfers both buffers and protein into a crystallization plate with best-in-class precision, accuracy, and reliability.
  • Syringes eliminate the need for costly and environmentally unsustainable disposal tip usage,

The ARI Crystal Gryphon protein crystallization pipettor can be used to set up sitting drop, hanging drop and microbatch plates with volumes down to 100nL.  The system consists of a 96 channel syringe head for dispensing buffer solutions and a non-contact protein dispenser.  It comes complete with a computer and easy-to-use drag-and-drop software.

By combining a 96-channel head with a single-channel protein dispense head, a 96-well plate can be set up and sealed in less than 1 minute.  This assures that evaporation will not affect your assays.

An optional 24-channel head is available for setting up optimization plates.  Using this head with the INTELLI-PLATE™ 24-4, you can set up 4 optimization assays with each buffer solution.

Specifications

The ARI Crystal Gryphon comes as a complete system with the following accessories:

  • Computer, mouse, and mouse pad
  • Multi-seat software license
  • Power cord
  • 4 outlet surger suppressor (115v only)
  • Computer cables and adapters
  • Syringe wash system
  • Nano wash system
  • Spare nano nozzle
  • Two spare syringes
96 Head for buffer solutions 100 nL to 100 µL
LCP Dispense Head 25 nL to 2 µL
Protein dispense Head 50 nL to 100 µL
Dispense specs are CVs < 5%
Base 20(51)h x 23(59)w x 23(59)d  in(cm)

68 lbs, 31 Kg

Wash 13(33)h x 6.5(17)w x 14(36)d  in(cm)

5.5 lbs, 2.5 Kg

Protein head 9.5(24)h x 6(15)w x 16(41)d  in(cm)

18.5 lbs, 8.4 Kg

Base 120/240 Vac, 3 A, 50/60 Hz
Wash 120/240 Vac, 2 A, 50/60 Hz
Protein head 120/240 Vac, 1.5 A, 50/60 Hz
Operating Systems Windows  10 or 11

Applications

Protein Crystallization

Tissue Typing

Membrane Spotting

Kit Manufacturing

Accessories

 
LCP Syringe

LCP syringe for the Gryphon is designed to self-align and easily snap into place on the Gryphon.

620-1005-02   50 uL Syringe

620-1005-03   100 uL Syringe

620-1100-01   ARI Dispense Needle Assy, Short, .250 (3/pk)

620-1100-02   ARI Dispense Needle Assy, Long, .900 (3/pk)  For use with seeding

ARI Crystal Gryphon Accessories  LCP Coupling and Ferrule

These ferrules are for use with the Gryphon syringes and the LCP Mixer.

The ferrules are shown left to right in the adjacent image. The LCP Mixer and the Gryphon use the same ferrules, but different couplings.

620-1200-01  ARI-ARI Mix Ferrule Assy w/ Coupling

620-1200-02  ARI-Hamilton Mix Ferrule Assy w/ Coupling

620-1200-03  Hamilton-Hamilton Mix Ferrule Assy w/ Coupling

ARI Crystal Gryphon Accessories  LCP Coupling 

The larger coupling is for use on the LCP Mixer. The smaller coupling is used with mixing on the Gryphon LCP or manually.

620-1600-01   Replacement LCP Syringe Coupling (3/pk)

620-1600-02   Replacement LCP Syringe Mixer Coupling

ARI Crystal Gryphon Accessories  LCP Mixing Station

Spend your time screening your protein, not mixing your LCP. The small, quiet, and easy-to-use LCP Mixing Station provides consistent mixing from sample to sample, user to user, and day to day. Simply loading the syringe automatically sets the mixing volume so that only the sample volume is mixed. Learn more.

620-4000-00  LCP Mixing Station

620-1600-02   Replacement LCP Syringe Mixer Coupling

620-1300-01  ARI-ARI Mixer Ferrule Assy w/ Coupling

620-1300-02  ARI-Hamilton Mixer Ferrule Assy w/ Coupling

620-1300-03  Hamilton-Hamilton Mixer Ferrule Assy w/ Coupling

Protein crystallization pipettor Accessories 
Hanging Drop Seals and Fixture

UV-compatible seals and a fixture for aligning the seals on your plate and to the deck of your Gryphon or Phoenix are available. Contact us for a sample to evaluate.

600-4004-00   Hanging Drop Tool

600-4006-00   Hanging Drop Seals (50 per pack)

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