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So far Heath Thomas has created 47 blog entries.

How To Map An ELISA Plate

A map of an ELISA plate is essentially a template of the 96 wells found on a standard ELISA plate. With 96 wells, each containing an individual sample, it is critical to track exactly what has been placed in each well. An ELISA plate map helps to do exactly that. An ELISA plate map is [...]

2021-09-21T17:14:10-04:00September 21st, 2021|Comments Off on How To Map An ELISA Plate

Describing Colony Morphology: A Basic Guide

Did you know that the first microscope was essentially just two types of lenses stacked on one another? Before the invention of even a barebones microscope in the 16th century, scientists often relied on the power of observation via the naked eye to come to their hypothesis. Bacterial colonies, for example, were identified based on [...]

2021-09-14T17:34:28-04:00September 14th, 2021|Comments Off on Describing Colony Morphology: A Basic Guide

Top 5 Features of an Automated pH Meter

An automated pH meter is a device that measures a sample from each of the wells in a microplate plate and measures the pH. Most commonly used are 96 well microplates, although other microplates such as 48 and 24 well plates are used. Throughout the entire process, there is no technician involvement, and when the [...]

2021-09-07T16:46:51-04:00September 7th, 2021|Comments Off on Top 5 Features of an Automated pH Meter

Drug Stability Testing and Analysis

Stability testing of pharmaceutical products such as medications in pills, creams, liquids, etc., is a critical characteristic of any pharmaceutical agent. Stability not only indicates how long medication is effective when sitting on a shelf but patient safety can also be threatened when some medications break down over time or when exposed to light or [...]

2021-08-31T16:53:24-04:00August 31st, 2021|Comments Off on Drug Stability Testing and Analysis

pH For Stability Testing and Analysis

Microplate Washer ELISA For over 100 years, pH has been an invaluable tool for measuring the acidity of solutions. Based on a logarithmic scale from 0 - 14, the pH scale made what was once a difficult calculation, an easy to understand measure of free hydrogen protons (H+) in a solution. This simple scale is [...]

2021-08-26T14:52:50-04:00August 24th, 2021|Comments Off on pH For Stability Testing and Analysis

Bacterial Colony Morphology 101

Microplate Washer ELISA Bacterial colonies are an important component of microbiology that remains relevant to this day and probably will always stay that way. These colonies are used for medical research, development of pharmaceuticals, use in the food industry (the safe ones, naturally) and more. Once a bacterial colony is cultivated, the first thing to [...]

2021-08-17T15:36:54-04:00August 17th, 2021|Comments Off on Bacterial Colony Morphology 101

Serial Dilution Method In ELISA: What & How

ELISA is based on the interaction of antibodies and antigens where the antibodies attach to specific proteins or nucleic acids. With measurable reporter molecules attached to the antibodies, it is possible to measure the amount of protein or nucleic acid present. Serial dilution ELISA is an important part of testing whenever examining an unknown peptide [...]

2021-08-10T12:27:46-04:00August 10th, 2021|Comments Off on Serial Dilution Method In ELISA: What & How

qPCR Analysis Software: Uses & Benefits

Initial Problems Developing Automated Liquid Handling Robots The “q” in qPCR stands for quantitative. Over the past 20 years, the tremendous advances made by the development of the polymerase chain reaction (PCR) have been augmented by the ability to quantify nucleic acid replication with qPCR analysis software in real-time. With qPCR analysis software, everything from [...]

2021-08-03T13:25:33-04:00August 3rd, 2021|Comments Off on qPCR Analysis Software: Uses & Benefits

The Basics of Protein Expression and Purification

Initial Problems Developing Automated Liquid Handling Robots Whether human, plant, or bacteria, proteins play a vital role in every living cell's structure and function in our universe. Proteins were first discovered in 1838 by the Swedish chemist Jöns Jacob Berzelius who recognized the critical importance of these substances for life. Consequently, he chose the name [...]

2021-07-27T01:36:37-04:00July 27th, 2021|Comments Off on The Basics of Protein Expression and Purification

Components of a Liquid Handling System

In modern science and pharmaceutical laboratories, tiny amounts of liquid must be transferred many times to perform everything from genetic testing to drug screens. As science has improved, the amount of liquid needed for accurate testing has been reduced to low microliter and even nanoliter amounts. Trying to transfer these very small quantities fully and [...]

2021-07-20T16:15:23-04:00July 20th, 2021|Comments Off on Components of a Liquid Handling System
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