Call (973) 376-7400 Request a Quote
Ahead of the Curve.

DNA Transformation into Bacteria

Hudson Robotics equipment

DNA Transformation into Bacteria

Transformation, in which DNA is incorporated into a bacterial cell, is a key step in many biological and pharmaceutical applications.  Modified DNA can change the phenotypic characteristics of an organism, such as thermal stability, or it can be used to turn a bacteria into a drug-producing factory.  The process requires cells that can pass DNA through their cell wall, ie. competent cells.  Currently, the two general approaches to transform cells are heat-shock and electroporation.  Hudson has developed a number of automated systems that transform Bacterial cells using heat shock-based protocols.

Synthetic Biology Pipeline


Transformation is a key part of the following Applications Pipelines that we support:

SOLO Liquid Handler

SOLO Liquid Handler

The Hudson SOLO™ liquid handling robot is an automated pipettor that can do anything expected of a hand-held pipettor perfectly, at about half the cost of other laboratory robotics platforms, without human error. The Solo works well below 1ul (1-3ul CV=1%; 0.25ul CV=4%). The Solo will fit into most biological safety cabinets and fume hoods. The SOLO can be loaded and operated manually, but is also compatible with robot loading systems from most manufacturers, including our PlateCrane EX.

RapidPick MP: 20 Pin Colony Picker

RapidPick MP: 20 Pin Colony Picker

The RapidPick MP is the fastest, most accurate automated multi-pin colony picking system in the world with over 99% inoculation rates and typical speeds of picking over 2,400 bacterial colonies per hour.  The small footprint saves lab space, allows for easy cleaning and fits into microbiome chambers and biosafety hoods. The RapiPick MP is at the heart of the Complete and Lite systems which include robotic plate loading, media filling as well as other features, such as plate sealing in the RapidPick Complete Workcell. 

The RapidPick MP is intended for researchers who need the accuracy and high outgrowth rates of the RapidPick colony-picker, but whose workload doesn’t require the added automation available in the Complete or Lite systems.    

Automated Bacterial Transformation and Plating using the Hudson Solo Pipettor

Request a Quote